.
 
.

Handbook of Adaptive Designs in Pharmaceutical And Clinical Development

Avtor:

.
Redna cena: 139,12 €
Predvideni rok dobave: 14-21 dni
.
.
Količina:  
.
Strošek dostave je enoten za celo Slovenijo in znaša 2,95 €, ne glede na količino in vrsto kupljenih izdelkov.

Številni izdelki imajo oznako "brezplačna dostava", kar pomeni, da v prmeru nakupa takšnega izdelka poštnine ne boste plačali. 

Več o dostavi
Emka.si omogoča naslednje načine plačila:
  • z gotovino ob prevzemu (velja le za fizične osebe),
  • s plačilno oziroma kreditno kartico (Mastercard, Visa, ActivaMaestro, Activa, Diners, American Express),
  • s storitvijo Moneta (Mobitel in Simobil)
  • Plačilo po predračunu (pravne osebe)
  • Račun z odlogom plačila (za javna podjetja)
Več o plačilih

Pri vsakem izdelku je naveden predviden rok dostave. Glede na to katere izdelke izberete, se vam pri oddaji naročila prikaže tudi končni predviden datum dobave vašega pakete.

Večino izdelkov dostavljamo iz lastne zaloge, zato so naši dobavni roki zelo kratki.

Ko vam bomo poslali paket boste o tem obveščeni tudi po emailu. V emailu bo navedena številka vašega paketa ter povezava do Pošte Slovenije, kjer boste lahko preverili natančen status dostave.

Več o dostavi

To je spletna cena
Shrani v seznam želja
.

.

Opis

In response to the US FDA’s Critical Path Initiative, innovative adaptive designs are being used more and more in clinical trials due to their flexibility and efficiency, especially during early phase development. Handbook of Adaptive Designs in Pharmaceutical and Clinical Development provides a comprehensive and unified presentation of the principles and latest statistical methodologies used when modifying trial procedures based on accrued data of ongoing clinical trials. The book also gives a well-balanced summary of current regulatory perspectives.


 


The first several chapters focus on the fundamental theory behind adaptive trial design, the application of the Bayesian approach to adaptive designs, and the impact of potential population shift due to protocol amendments. The book then presents a variety of statistical methods for group sequential design, classical design, dose-finding trials, Phase I/II and Phase II/III seamless adaptive designs, multiple stage seamless adaptive trial design, adaptive randomization trials, hypotheses-adaptive design, and treatment-adaptive design. It also covers predictive biomarker diagnostics for new drug development, clinical strategies for endpoint selection in translational research, the role of independent data monitoring committees in adaptive clinical trials, the enrichment process in targeted clinical trials for personalized medicine, applications of adaptive designs that use genomic or genetic information, adaptive trial simulation, and the efficiency of adaptive design. The final chapters discuss case studies as well as standard operating procedures for good adaptive practices.


 


With contributions from leading clinical researchers in the pharmaceutical industry, academia, and regulatory agencies, this handbook offers an up-to-date, complete treatment of the principles and methods of adaptive design and analysis. Along with reviewing recent developments, it examines issues commonly encountered when applying adaptive design methods in clinical trials.

.
.
.

O avtorju - Annpey Pong

Obvestite me o novi knjigi tega avtorja

Želite, da vas po elektronski pošti obvestimo, ko izide nova knjiga ali ponatis katere od knjig tega avtorja?

DA - obveščajte me o novostih avtorja
.
.
.
.

Mnenja kupcev

  0  ocen:
5 zvezdice
0%
(0)
4 zvezdice
0%
(0)
3 zvezdice
0%
(0)
2 zvezdice
0%
(0)
1 zvezdica
0%
(0)
Povprečna ocena kupcev:
Ocena kupcev: 0
(0 ocen uporabnikov )
.
Ocenite izdelek s klikom na zvezdice:
 
.
.
.
.
.

Oznake kupcev o tem izdelku

Kliknite na posamezno oznako za prikaz vseh izdelkov označenih s to oznako:

Dodaj oznako:

Dodaj
.